The risk of transmission of SARS-CoV-2 through blood and blood products: The current state of knowledge (international review)

Introduction: Severe acute reparatory syndrome coronavirus-2 (SARS-CoV-2) is a recently emerged coronavirus, and infection with SARS-CoV-2 can remain asymptomatic or lead to coronavirus disease. Clinical pictures range from pre-clinical stage severe pneumonia. The presence of this could pose problem for the management transfusion chain as donors employees may become infected during their travels activities, exponentially increase number but individuals. So, threat blood safety. Aim: In study, we want provide necessary information about real risk transmission via products. It constitutes one most controversial topics several critical questions which both professionals in centers health services seek apparent answers. Methods: literature review where have consulted relevant papers articles through For purpose, scientific research sites were using key terms search strategy. Thus, compiled presented (i) positions international societies public bodies; (ii) available data date on detecting RNA COVID-19 patients donors; (iii) published cases products confirmed positive after donation process recipients these Results: All stipulated that new infectious agent. No sufficient exclude certainty transmission, remains theoretical risk. has been detected very lowly, virus infectivity not donors. Reported product provided any evidence recipients. As precautionary measure, set up measures reduce ensure safety Strengthening hemovigilance system post-donation an essential link pandemic. Conclusion: transfusion-transmitted still theoretical. This novel be no direct raises serious issues general supply. taken by secure against are preventive should consider need availability